Nickel-Catalyzed C-Alkylation of Nitroalkanes with Unactivated Alkyl Iodides

Jacs
Nickel-Catalyzed C-Alkylation of Nitroalkanes with Unactivated Alkyl Iodides:Enabled by nickel catalysis, a mild and general catalytic method for C-alkylation of nitroalkanes with unactivated alkyl iodides is described. Compatible with primary, secondary, and tertiary alkyl iodides; and tolerant of a wide range of functional groups, this method allows rapid access to diverse nitroalkanes.

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