Visible-light excitation of iminium ions enables the enantioselective catalytic β-alkylation of enals

Naturechem
Visible-light excitation of iminium ions enables the enantioselective catalytic β-alkylation of enals
Mattia Silvi, Charlie Verrier, Yannick P. Rey, Luca Buzzetti & Paolo Melchiorre
Chiral iminium ions generated from an amine catalyst and enals are key organocatalytic intermediates in thermal asymmetric processes. Now, visible-light excitation of these iminium ions can turn these compounds into strong oxidants to enable enantioselective photochemical β-alkylations of enals with silanes, which are unachievable via conventional ground state pathways.
 

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