Stereoselective Synthesis of Tetrasubstituted Alkenes via a Cp*CoIII‐Catalyzed C−H Alkenylation/Directing Group Migration Sequence

Angewchem
Stereoselective Synthesis of Tetrasubstituted Alkenes via a Cp*CoIII‐Catalyzed C−H Alkenylation/Directing Group Migration Sequence: A highly atom economical and stereoselective synthesis of tetrasubstituted α,β‐unsaturated amides was achieved by a Cp*CoIII‐catalyzed C−H alkenylation/directing group migration sequence. A carbamoyl directing group, which is typically removed after C−H functionalization, worked as an internal acylating agent and migrated onto the alkene moiety of the product.

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