A Rhodium(II)‐Catalyzed Formal [4 1]‐Cycloaddition toward Spirooxindole Pyrrolone Construction Employing Vinyl Isocyanates as 1,4‐Dipoles

Angewchem
A Rhodium(II)‐Catalyzed Formal [4 1]‐Cycloaddition toward Spirooxindole Pyrrolone Construction Employing Vinyl Isocyanates as 1,4‐Dipoles: A RhII‐catalyzed, formal [4+1]‐cycloaddition between diazooxindoles as electrophilic C1 synthons and 1,3‐heterodienes for the construction of spirooxindole pyrrolones is described. Employing vinyl isocyanates as 1,4-dipoles, the cycloannulation occurs under relatively mild conditions and provides the corresponding pyrrolones in good to excellent yields.

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